John E. Dowling, the Gordon and Llura Gund Professor of Neurosciences at Harvard, was awarded the Glenn A. Fry Medal in Physiological Optics during a ceremony at the Great Lakes Vision Research Conference in Columbus, Ohio, on Nov. 21.During the 1970s and 1980s, Dowling, who is now president of the Corporation of the Marine Biological Laboratory in Woods Hole, Mass., was at the forefront of research into the identification of the excitatory and inhibitory neurotransmitters that mediated retinal synaptic communication. He also helped establish the concept of neuromodulation in the retina and was involved in seminal studies that investigated the role of dopamine as a neuromodulator in the retina. In the 1990s, he began working with zebrafish in order to identify the genes important in regulating both visual sensitivity and retinal development.
Read Full Story Tuberculosis is the world’s deadliest infectious disease, killing 1.7 million people each year. There has been little progress lowering the rate of new cases of the disease — and in some countries, it may be increasing. In an editorial, infectious disease expert Barry Bloom of Harvard T.H. Chan School of Public Health outlines the health system failures behind the global TB epidemic, and argues that systems’ ability to diagnose and treat TB must be strengthened to control the disease.The editorial was published in the Jan. 18, 2018 issue of the New England Journal of Medicine.Current TB control strategies largely depend on patients with symptoms seeking treatment, but this can miss a third of cases, writes Bloom, Joan L. and Julius H. Jacobson Research Professor of Public Health. There is no inexpensive diagnostic test for TB, increasing the chance in low-income countries that cases will be missed. Although an effective treatment regime exists for patients with drug-sensitive TB, it requires multiple drugs given for six to nine months, which can be a significant burden. According to Bloom, only 45 percent of patients with any form of tuberculosis complete treatment by one year.In an accompanying paper, researchers found that by studying household contacts of TB patients in Vietnam, they were better able to detect early and asymptomatic cases.Bloom writes in his editorial that this is an important new finding. “At a time when support for biomedical research and foreign aid is threatened, better tools, including active case finding in high-burden countries, are critically needed to improve control of the largest cause of death from an infectious disease and to improve the lives of millions of people.”
BY DOMINIQUE GABRIEL BAÑAGA BACOLOD City – Authorities here plan to subject all mendicant Badjaos to reverse transcription-polymerase chain reaction (RTC-PCR) test possible coronavirus disease 2019 (COVID-19) infection. Pacita Tero, head of the Department of Social Services and Development (DSSD), proposed this move following the recovery of the remains of an unidentified man along Palanca Street in the city’s Bredco port earlier this week.Tero expressed worry that around 70 Badjaos they counted roaming this city may have already either contracted the SARS-coV-2, the virus that causes COVID-19, or may have become carriers of the virus.Tero said she has already forwarded the proposal to CHO Environmental Sanitation Division head Dr. Grace Tan, to have the Badjaos in the city undergo Covid-19 testing.Plans have also been made for the Badjaos to be returned home to Jolo, Sulu after conducting the RT-PCR tests, however, transporting them would be a problem as there are currently no trips between Bacolod City heading to Mindanao.The only available trips that would take the Badjaos home is in Dumaguete City, Negros Oriental, although no one is allowed to cross as the borders between Negros Occidental and Negros Oriental are still closed.However, Tero said the provincial government of Negros Oriental has agreed to serve as a holding area for Badjaos if there is no one yet from Zamboanga that would pick them up.Earlier on Wednesday, a traffic enforcer discovered the naked man’s lifeless body lying underneath a tree by a near the Bredco port area.Investigation revealed that the individual was believed to be homeless and suffering from mental illness.The remains were no longer autopsied to determine the cause of death, although police believe the individual likely died of natural causes as he had no wounds found on his body./PN