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Don’t edit embryos, researchers warn

first_imgScientists should refrain from studies that alter the genome of human embryos, sperm, or egg cells, researchers warn in a commentary published today in Nature.In it, they sound the alarm about new genome-editing techniques known as CRISPR and zinc-finger nucleases that make it much easier for scientists to delete, add, or change specific genes. These tools have made it possible to make better animal models of disease and more easily study the role of individual genes. They also hold the promise of correcting gene mutations in patients, whether in blood cells, muscle cells, or tumor cells.But scientists have also used the technology to make genetically altered monkeys. And there are rumors that some researchers are trying the same technique on human embryos, MIT Technology Review reports.Sign up for our daily newsletterGet more great content like this delivered right to you!Country *AfghanistanAland IslandsAlbaniaAlgeriaAndorraAngolaAnguillaAntarcticaAntigua and BarbudaArgentinaArmeniaArubaAustraliaAustriaAzerbaijanBahamasBahrainBangladeshBarbadosBelarusBelgiumBelizeBeninBermudaBhutanBolivia, Plurinational State ofBonaire, Sint Eustatius and SabaBosnia and HerzegovinaBotswanaBouvet IslandBrazilBritish Indian Ocean TerritoryBrunei DarussalamBulgariaBurkina FasoBurundiCambodiaCameroonCanadaCape VerdeCayman IslandsCentral African RepublicChadChileChinaChristmas IslandCocos (Keeling) IslandsColombiaComorosCongoCongo, The Democratic Republic of theCook IslandsCosta RicaCote D’IvoireCroatiaCubaCuraçaoCyprusCzech RepublicDenmarkDjiboutiDominicaDominican RepublicEcuadorEgyptEl SalvadorEquatorial GuineaEritreaEstoniaEthiopiaFalkland Islands (Malvinas)Faroe IslandsFijiFinlandFranceFrench GuianaFrench PolynesiaFrench Southern TerritoriesGabonGambiaGeorgiaGermanyGhanaGibraltarGreeceGreenlandGrenadaGuadeloupeGuatemalaGuernseyGuineaGuinea-BissauGuyanaHaitiHeard Island and Mcdonald IslandsHoly See (Vatican City State)HondurasHong KongHungaryIcelandIndiaIndonesiaIran, Islamic Republic ofIraqIrelandIsle of ManIsraelItalyJamaicaJapanJerseyJordanKazakhstanKenyaKiribatiKorea, Democratic People’s Republic ofKorea, Republic ofKuwaitKyrgyzstanLao People’s Democratic RepublicLatviaLebanonLesothoLiberiaLibyan Arab JamahiriyaLiechtensteinLithuaniaLuxembourgMacaoMacedonia, The Former Yugoslav Republic ofMadagascarMalawiMalaysiaMaldivesMaliMaltaMartiniqueMauritaniaMauritiusMayotteMexicoMoldova, Republic ofMonacoMongoliaMontenegroMontserratMoroccoMozambiqueMyanmarNamibiaNauruNepalNetherlandsNew CaledoniaNew ZealandNicaraguaNigerNigeriaNiueNorfolk IslandNorwayOmanPakistanPalestinianPanamaPapua New GuineaParaguayPeruPhilippinesPitcairnPolandPortugalQatarReunionRomaniaRussian FederationRWANDASaint Barthélemy Saint Helena, Ascension and Tristan da CunhaSaint Kitts and NevisSaint LuciaSaint Martin (French part)Saint Pierre and MiquelonSaint Vincent and the GrenadinesSamoaSan MarinoSao Tome and PrincipeSaudi ArabiaSenegalSerbiaSeychellesSierra LeoneSingaporeSint Maarten (Dutch part)SlovakiaSloveniaSolomon IslandsSomaliaSouth AfricaSouth Georgia and the South Sandwich IslandsSouth SudanSpainSri LankaSudanSurinameSvalbard and Jan MayenSwazilandSwedenSwitzerlandSyrian Arab RepublicTaiwanTajikistanTanzania, United Republic ofThailandTimor-LesteTogoTokelauTongaTrinidad and TobagoTunisiaTurkeyTurkmenistanTurks and Caicos IslandsTuvaluUgandaUkraineUnited Arab EmiratesUnited KingdomUnited StatesUruguayUzbekistanVanuatuVenezuela, Bolivarian Republic ofVietnamVirgin Islands, BritishWallis and FutunaWestern SaharaYemenZambiaZimbabweI also wish to receive emails from AAAS/Science and Science advertisers, including information on products, services and special offers which may include but are not limited to news, careers information & upcoming events.Required fields are included by an asterisk(*)That is unsafe and unethical, say Edward Lanphier and four other researchers in their commentary. Ethically justifiable applications “are moot until it becomes possible to demonstrate safe outcomes and obtain reproducible data over multiple generations,” they write. They call for a moratorium on any experiments that would edit genes in sperm cells, egg cells, or embryos while scientists publicly debate the scientific and ethical consequences of such experiments. The recent discussion of mitochondrial DNA replacement therapy in the United Kingdom could be a model, they suggest.They hope that such a discussion would help the public understand the difference between genome editing in a person’s somatic cells—cells other than sperm and egg cells—and editing in cells that could pass the changes on to future generations, says Lanphier, who is president and CEO of Sangamo BioSciences in Richmond, California, a company that hopes to use gene-editing technology to treat patients. “There’s an important and clear ethical boundary between genome editing in somatic cells versus in the germ line.”George Daley, a stem cell researcher at Boston Children’s Hospital and Harvard Medical School, agrees that a public debate is important. Among scientists, he says, there is broad consensus that at the moment “it’s far too premature and we know far too little about the safety to make any attempts” at modifying germ cells or embryos. But that will eventually change, he says. “There needs to be broad public debate and discussion about what, if any, are the permissible uses of the technology.”last_img read more

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Despite initial skepticism Londoners are putting on their best show at Olympics

first_imgLike many Londoners, I had not been looking forward to the Olympics. Over the past years, the cost of the project rose to an astronomical 9 billion (Rs 76,500 crore) to be paid from our taxes-at enormous inconvenience to us. Hundreds of thousands of extra visitors will be in our,Like many Londoners, I had not been looking forward to the Olympics. Over the past years, the cost of the project rose to an astronomical 9 billion (Rs 76,500 crore) to be paid from our taxes-at enormous inconvenience to us. Hundreds of thousands of extra visitors will be in our city, adding even more pressure to its groaning transport services and infrastructure, while Soviet-style zili lanes were established to enable chauffeur-driven sporting stars, bureaucrats and elite to be ferried quickly to the venues without being clogged in traffic with the rest of us. To add to the humiliation, we were then informed that ticketing for much of the Games would be monopolised by the suited, soulless, corpulent corporation-wallahs whose logos and branding were splashed all over our capital like a torrent of bird-droppings.Rather than a festival of sport and human endeavour, we braced ourselves for a fortnight’s celebration of capitalism. And on top of all that, we’ve had one of the dreariest, rain-sodden summers in memory. Our fears about the Olympics were perfectly articulated by a friend of mine who described the event as “a long, expensive party we’re not invited to, for which we’ve paid, during which we have to leave our car at home and walk everywhere.”Michelle Obama hugs basketball star Kobe Bryant after USA defeated France in a preliminary game.And the fears only rose as the Games started. Last week, the North Korean women’s football team took to the field as the authorities raised the South Korean flag above them. Surely, there isn’t a more sinister faux pas one can make during an international spectacle? This gaffe only made us cringe deeper when, on July 26, our bumbling shaggy-haired mayor, Boris Johnson, took to the stage in Hyde Park to shout banal sub-Obama declarations of “Are we ready? Yes, we are!”advertisementThe Olympics Opening Ceremony in London.And then came the opening ceremony. For all its wonder and anarchic creativity, the greatest miracle it wrought-more splendid than the fiery Olympic rings it forged so magnificently -was that it transformed our souls. Suddenly, confronted by the berserk, magical vision of Danny Boyle, weaving every facet of our history into the greatest show the world has seen, we were shaken out of our dour cynicism. We are, as Boyle held his Olympian mirror to us, an incredible people. The industrial drive of the modern world, the moral ambition of universal suffrage, the mad middle-finger-to-the-world spirit of pop culture-all of this has its origins in our city, capital of a tiny island that has, more than any other in history, punched so mightily above its weight.Click here to EnlargeAnd we have been inspired because Boyle’s ceremony, despite its global audience, spoke specifically to the hearts of one community: we, the people of London-all eight million of us! I cannot begin to list the variety of in-jokes that littered his spectacle, lost on the wider world, but which tickled us pink. The most hilarious was the Sex Pistols’ rendition of God Save The Queen being played as Her Majesty entered the bowl, stopping a hair’s breadth short of the line that excoriates her for heading a “fascist regime.” Just as funny was the sight of David Cameron having to wear his proudest smile as the show turned into a paean for the National Health Service and the sort of socialist big-statism that he has long opposed. It was a performance filled with wit and subversion, featured every race and colour of our capital’s populace, gave prime billing to the young black rapper, Dizzee Rascal, a working-class youth icon, who sang his aptly-titled anthem, Bonkers, interspersed with a Punjabi song by A.R. Rahman.Click here to EnlargeYes, the expense of the Olympics is extortionate. It was foisted on us without any consultation. Then again, we never chose to fight Hitler either. But when he brought his bombs to London, the world saw what mettle and love for life we have. And now that the Olympics are here up and running, we’re behind it as if we have mortgaged our homes to bet on every race, leap, toss and flip that’s part of this whole shebang.US swimmer Ryan Lochte in the Men’s 200m backstroke event at the Aquatics centre.My friend Fleur Emery, a dynamic businesswoman, between cutting deals and chasing money, is sharing every detail of the women’s diving contest on Facebook. “Thanks to the BBC,” she’s declared, “I now know exactly how to do a flunge.” Yesterday, her obsession was with women’s cycling and now, via Facebook, her friends can also discuss the merits of a well-executed peloton (it’s a huddle of riders in team cycling), as if we had been lifelong enthusiasts. She’s not the only one. The wheels of global capitalism are turning slower for these two weeks as London’s workers and entrepreneurs are skipping mornings, even days, off work to partake of such sporting acana as men’s team archery and women’s powerlifting.But while we may be skiving off, the merchants of west London are reeling with joy as affluent, middle-aged tourists from across the world are heaving in to shop any piece of ridiculously overpriced tat that a Chinese sweatshop can produce. But it’s sold in Britain, and has the Union Jack emblazoned on it, so shall more than suffice as an ‘authentic’ memento of a wonderful Olympics.advertisementKate Middleton and Prince William at an equestrian event.These shoppers could not have come at a better time. The Chancellor, George Osborne, must have been fingering his phial of cyanide when latest figures showed that Britain’s recession is actually three times worse than had been predicted. But the savings of the global middle classes are currently flooding here for a fortnight, so he can breathe easy for a week or two at least. What greater respect could be paid to the copulation of sport and capitalism, than the fact that McDonald’s has introduced a new uniform for the Olympics, replete with athletic hoodies and tennis collars. The world’s foremost purveyors of cholesterol, which underpins the obesity epidemic of the West, are the standard bearers of human excellence.In this time of recession and blame-mongering, the Olympics is the only thing in Britain that has universal political support. The Labour Party under Tony Blair won the bid to become hosts seven years ago, while the Tories have thrown their weight behind it since taking over the government. It was one of the more exquisite ironies of the night, that David Cameron had actually raised the budget of the opening ceremony to 27 million (Rs 229.50 crore) -only to then see it made into a showcase for Boyle’s left-wing politics. But even I raised an eyebrow at the scene of a bucolic pre-industrial England, peopled with so many black and brown people.The only protests thus far have been to decry the empty seats, as various federations failed to use their quotas. Londoners are livid at seeing gaps in the crowd, after so many had failed to get tickets through the labyrinthine official process. These will soon be filled, it seems, by the military and students.The Games are also brimming with simmering tensions and sporting rivalries. Not least among British athletes themselves. Several non-English players in the British football team have refused to sing the national anthem before matches (It’s also the English anthem. The Scots, Welsh and Northern Irish have their own). Possibly the biggest rivalry during the Games has been between Ralph Lauren, designer of the US team’s outfits, and Stella McCartney, who designed Britain’s. While the stylish, preppie look of the US team has been widely admired, McCartney’s creation has been derided for its glitz, hoodies and cut-off shorts. Many people think it makes our team look like ‘chavs’-members of the sportswear-clad urban underclass. For us fashion-conscious Brits, Usain Bolt’s quest for gold against Yohan Blake is, by comparison, a mere sideshow.advertisementIndia’s role at the Olympics will pass most Londoners by, given that events Indians excel at are not the most high profile over here. But the lady who had the gall to walk alongside the team during the opening ceremony is admired for her temerity. Gatecrashing is an art form to the British, and she is walking in the footsteps of Karl Power, a national hero who has inveigled himself into English rugby and cricket team photos, as well as with Manchester United in a Champions League final. She could indeed become another British oddball hero, like the volunteer who has become a YouTube sensation after her cheeky quips on a megaphone, telling those without tickets how they will one day tell their grandchildren how lucky they were to “hear the Olympics”, got uploaded.Londoners as a whole have finally warmed to the Olympics. We didn’t want it, and we groaned at the thought of it. But now that it’s begun, we will show the world what sports we are.- The author is a freelance writer and journalistlast_img read more

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Best practices for building scalable cloud applications

first_img Maria Thomas says: Share this:TwitterFacebookLinkedInMoreRedditTumblrPinterestWhatsAppSkypePocketTelegram Did you know that the database tier is the biggest bottleneck of any given application? As your database tier demands are always fluctuating, it is not feasible to employ a one-size-fits-all approach when building a scalable cloud application. Let’s take a look at the best practices for architecting your database tier for high availability and resilience:Scaling Up If your enterprise is in the nascent stage of an application, the load on the database is relatively lighter and a smaller instance size can be adequate for both master and slave databases. As and when an enterprise grows, the load increases and the master database needs to be migrated to a bigger instance size for additional power, memory and I/O throughput.For effective management of database requests, complex queries, multiple tables, and additional memory are needed to accelerate the response time. The disk I/O demands of any application can be greatly reduced by keeping the working database contained entirely in memory. The performance gains realized from vertical scaling far outweigh the expenses incurred on instance sizes.Using a database load balancing software that facilitates the migration of the database from a smaller instance size to a larger one without needing any changes to the application even as the traffic escalates will mitigate the expenses of larger instances and minimize downtime.Scaling Out If you have a master database, implementing additional slave databases will work to increase the availability and reliability of apps and facilitate horizontal scaling. Using a proxy mechanism with a database load balancing software will distribute TCP traffic appropriately and direct read and write requests properly. Making the application master/slave aware with access information available to both needs SQL server load balancing that can accommodate variable workloads and distribute all read requests uniformly among available slaves.Database Scaling       As an application’s lifecycle progresses it needs to become more scalable and agile at every a larger number of users will be interacting with it. The resource requirements of every database tier increase with time and this creates the need for a well-planned and implemented database design that facilitates horizontal and vertical scaling of database tier to varying degrees.Database Sharding Sharding involves the partitioning of database tables and placement of these distinct pieces on separate servers. This approach works similar to a proxy server where the reads and writes are dispersed across multiple servers to reduce the load on an individual database server. It is recommended to remove the sharding server and modify the application to make it aware of the implementation so that the app can connect to the appropriate server on the basis of the object that is to be accessed. Sharding facilitates an even distribution of queries and improves throughput. If your app relies on cross-table joins and involves multiple servers, sharding may not serve your purpose efficiently.Why a Load Balancing Software Makes Sense Scaling every tier individually can be downright complex and challenging because the architecture of every application comes with a unique set of advantages and limitations. A load balancing software can best handle peaks and dips in traffic by adding and removing virtual machines accordingly. Scale your database capacity with a load balancer and meet anticipated and unexpected demands efficiently.Since the database tier is the biggest bottleneck in building a scalable application, a load balancer solution that ensures easy deployments across multiple clouds, monitors servers, and evenly distributes traffic to servers that are fully-equipped to handle requests makes perfect sense. Boost your database performance and streamline the job of your app developers with a load balancing solution that automates all your management tasks, integrates new applications, accelerates your response time and ensures better security.Tony Branson is a self-proclaimed tech geek, with a passion for ScaleArc’s disruptive technology innovation in database load balancing. Tony has a passion for dissecting tech topics such as transparent failover, centralized control, ACID compliance, database scalability and downtime effects. On his days off, he can be found watching sci-fi movies, rock climbing or volunteering. June 6, 2018 at 5:29 am 1 thought on “Best practices for building scalable cloud applications” Continue Reading Previous Money mangled the megabyteNext Funding your startup: A primer for techies Leave a Reply Cancel reply You must Register or Login to post a comment. This site uses Akismet to reduce spam. Learn how your comment data is processed. Log in to Reply “Cloud computing has always been a new concept to me until I gave a fine read to this post. The improvement of the security of cloud computing is a must in this world of social media today. nnLikewise, I collected some information about the IT support anlast_img read more

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India sweep mixed team titles to conclude best ever ISSF WC performance

first_imgIndia produced their best ever show at the ISSF World Cup after sweeping both the mixed team titles on Thursday for a total tally of five gold medals in Munich, Germany.India topped the medals tally with five gold and a silver, while second placed China bagged nine medals — two gold, two silver and five bronze medals.India gold medallists included Apurvi Chandela (10m Air Rifle Women), Rahi Sarnobat (25m Pistol Women) and Saurabh Chaudhary (10m Air Pistol Men), besides the Mixed Team titles won on the last day.The pair of Anjum Moudgil and Divyansh Singh Panwar first won the 10m Air Rifle mixed team gold, even as the teenage pair of Manu Bhaker and Saurabh Chaudhary backed them up with the 10m Air Pistol mixed team title, rounding off a dominating show by the Indian squad at the year’s third International Shooting Sport Federation world cup stage.In fact, in the Mixed Air Rifle, it was an all India gold medal match and Apurvi Chandela and Deepak Kumar landed the country its lone silver, going down to their compatriots 2-16.Manu and Saurabh, in the Air Pistol finals, found it a bit tough against the experienced Ukranian pair of Olena Kostevych and Oleh Omelchuk but they won 17-9 in the end.Anjum and Divyansh shot 629.1 in round one of their relay to qualify as the fourth team, 0.1 points ahead of Apurvi and Deepak, who made it through as fifth having finished second in their individual relay earlier.advertisementThe gold medallists again bettered their countrymates in round two, shooting a combined 631.9 to top the eight-team standings. Apurvi and Deepak followed them with an effort of 630.2, setting up an all India gold medal match-up.Meanwhile, the Belarussian pair of Maria Martynova and Ilia Charheika won a thrilling bronze medal match against the Austrian pair of Olivia Hofmann and Alexander Schmirl 16-14. The Belarussians were down 0-10 at one stage before staging a remarkable comeback.In the gold medal match, Anjum and Divyansh were dominant with Apurvi and Deepak winning just the first two-shot series.In the Air Pistol competition, Manu and Saurabh also made their intentions clear from round one itself, topping the 76-team field with a score of 586 and then doing an encore in round two with an even better 591.World record holder Saurabh shot a 100 in his last series.In the gold medal match, against a team, which had a former Olympic champion in Olena, Manu and Saurabh kept ahead of the game from the onset, maintaining a four-point gap throughout.There was a moment when the Ukranians picked up three out six points for a semblance of a fight back, but solid shooting by the young Indian pair, meant they had no chance.The event format consisted of a first qualification round of three series of 20-shots each with each team member allocated 10-shots per series. The top eight teams would then move to a second qualification round and have another round in the same format.The top two teams would then qualify for the gold medal match while the third and fourth best teams would compete for the bronze medal.In the match-ups, each member would get a single shot and the higher aggregate score was allotted two points. This series would continue and the first to 16-points was declared the winner.Also Read | Munich World Cup: Manu Bhaker secures Olympic quota in shootingAlso Read | ISSF Shooting World Cup: Saurabh Chaudhary smashes world record to put India on topAlso Seelast_img read more

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a month agoBournemouth manager Howe defends team selection for Burton Albion

first_imgAbout the authorFreddie TaylorShare the loveHave your say Bournemouth manager Howe defends team selection for Burton Albionby Freddie Taylora month agoSend to a friendShare the loveBournemouth boss Eddie Howe has defended his team selection for Wednesday’s shock loss to Burton Albion that ended their Carabao Cup run.The League One side collected a 2-0 victory in a match which saw the stadium floodlights turn off three times.Howe made 10 changes from Friday’s win over Southampton, but believes the Cherries should’ve still got the victory.He said: “I see it as an opportunity missed every game you don’t fulfil your potential and play the way you want to.”It’s desperately disappointing, we are kicking ourselves – we know we are a lot better than that. it didn’t really show in the match.”I think we lacked everything. We lacked quality on the ball, we lacked intensity off the ball, we lacked our usual swagger. Certainly, we will have a lot of reflection.”I need to go away, watch the game and pick the bones out of it.” last_img read more

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SWS Hands Over First Valemax Newbuilding to COSCOCS

first_imgChinese shipping giant China COSCO Shipping Corporation (COSCOCS) has taken delivery of its first 400,000 dwt very large ore carrier from Shanghai Waigaoqiao Shipbuilding (SWS).Handed over on January 11, the Singapore-flagged vessel is the first from the batch of ten VLOC ordered from the China State Shipbuilding Corporation’s (CSSC) shipyard in April 2016.The VLOC Yuan He Hai would transport ore cargoes for Brazilian miner Vale.Under a 27-year agreement signed between COSCOCS and Vale in March 2016, the company would transport 16 million tons of iron ore for Vale on an annual basis.The remaining newbuilds, all featuring a length of 362 meters and a width of 65 meters, are slated for delivery in 2018 and 2019.The shipping firm informed that the ships are green, environmentally-friendly, and energy-saving, with fuel consumption reduced by nearly 30%.World Maritime News Staff; Image Courtesy: China COSCO Shipping Corporationlast_img read more

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Rising maintenance cost closure of routes driving minibuses out of city

first_imgKolkata: The number of mini-buses plying across the city is declining fast, as the unions claim high maintenance cost and closure of beneficial routes are compelling owners to shelve their vehicles.”The number of mini-buses plying in and around Kolkata has reduced from 1,500 to 1,200 in the last 5 years,” said Avashesh Daw, general secretary of Mini-Bus Operators’ Coordination Committee. While the cost of a mini-bus is Rs 15 lakh, the EMI amount has climbed beyond the capacity of the owners. Also Read – Bengal family worships Muslim girl as Goddess Durga in Kumari PujaIt may be mentioned, however, that the mini-bus, which is a shortened version of its full-sized brethren, is quite cramped and don’t offer adequate space to passengers, who face a particularly harrowing time aboard them in summers. According to the revised mini-bus fare chart, a passenger traveling from zero to three km need to pay Rs 8. In the next stage, which covers distance from three to six km, a passenger needs to pay Rs 9. From six to 10 km, the fare is Rs 10, while between 10 km and 16 km, the fare is Rs 11. Also Read – Bengal civic volunteer dies in road mishap on national highwayThis apart, three profitable mini-bus routes have been closed. “Route number 115 (Bijoygarh-BBD Bagh), Route number 124 (Golf Green-BBD Bagh) and Route number 130 (Bijoygarh-Howrah) have been closed,” Daw pointed out. He reiterated that the maintenance cost of the vehicles has shot up threefold. Apart from that, the diesel cost and insurance amount have also increased a lot. To run a mini-bus, the maintenance cost per day currently stands at Rs 500. “We have talked with officials several times, but those meetings were not fruitful. We want that the government should set up a regulatory committee to rationalise the bus fare and diesel price. We want that the fare should be set up at par with the diesel price. If this situation continues then we will definitely die an unnatural death,” added Daw.last_img read more

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Ottawa starts fiscal year with 68million surplus but red ink is on

OTTAWA — The federal government started the fiscal year with the tiniest of budgetary surpluses, though the black ink is expected to turn very red in the coming months.The Finance Department’s monthly fiscal monitor released Friday reports that the government posted a $68-million surplus for April and May, just less than last year’s total over the same period.The federal government’s fiscal year runs from April 1 to March 31.Fears grow in Ottawa that Bank of Canada hiked rates too soonOdds of rate hike just went up — and so did the Canadian dollar by almost a full centThe surplus is not expected to last, however, as the Liberals have promised to run deep deficits over the coming years to finance major infrastructure work and more lucrative child benefits.The feds ended up running a $21.85-billion deficit last year, and have projected a $28.5-billion deficit this year.The Finance report shows that program expenses increased by six per cent, or more than $2.6 billion, in April and May compared to the same period last year.About half of the increase was due to more money being spent on benefits for the country’s growing number of seniors as well as the new Canada Child Benefit. Much of the rest was in the form of additional spending on federal departments and agencies.The growth in expenses outstripped the nearly $2.3-billion, or 4.7 per cent, increase in revenues, which included a major boost in money raised by the GST but only moderate gains in income tax.However, public debt charges were down by 7.1 per cent, or $312 million, which helped push the final total from red to black.The Liberals won the 2015 election on a platform that promised annual deficits of no more than $10 billion over the next couple of years, and to eliminate the deficit by 2019-20.They are now projecting double-digit deficits until at least 2021-22, and have not provided a timeline for when the budget will be balanced.The Liberals and opposition Conservatives have been locked in a long-running and bitter battle over the state of the country’s finances.Prime Minister Justin Trudeau has blamed the Tories for leaving his incoming Liberal government with an $18-billion hole to fill after the 2015 election.The Conservatives counter that their budget had a small surplus, and that the Liberals have been recklessly spending since coming to power.The Finance Department report was released the same day that Statistics Canada said the country’s economy grew by a surprisingly strong 0.6 per cent in May, thanks to the energy sector.That has raised expectations the Bank of Canada could raise its key interest rate again this year.With files from Craig Wong read more

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Beating the heat at Safari Niagara

The heat and humidity we’ve been experiencing is not only tough on people, but on animals too.Mia Gordon took a trip to Safari Niagara and found out that the animals there are also trying to beat the heat.00:00:00 | 00:00:00::Projekktor V1.3.09

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Kelloggs profit rises but revenue falls short as breakfast business falters

AddThis Sharing ButtonsShare to TwitterTwitterShare to FacebookFacebookShare to RedditRedditShare to 電子郵件Email by The Associated Press Posted Aug 1, 2013 8:51 am MDT NEW YORK, N.Y. – Kellogg Co.’s profit rose in the latest quarter, but its revenue fell short of expectations as its breakfast business struggled.The maker of Frosted Flakes, Pop Tarts and Eggo waffles said Thursday that its North American sales rose in the quarter, helped by its specialty foods and the acquisition of Pringle chips last year. But the key morning foods unit saw a 3.3 per cent decline, even as the company tried to get Americans to eat more cereal.Details weren’t immediately available on which products dragged down results in the morning foods unit.But Kellogg, based in Battle Creek, Mich., has been fighting to increase cereal sales as people toward on-the-go meals in the mornings. General Mills, which makes Cheerios, is facing a similar problem and is deploying a variety of tactics such as marketing children’s cereal to adults by playing on their nostalgia for brands such as Lucky Charms.Back at Kellogg, CEO John Bryant has noted in the past that the company needs to play up the nutritional benefits to get baby boomers and higher-income people to eat more cereal. That’s why the company recently introduced Raisin Bran with omega-3 and a multigrain version of Special K.To expand into the salty snacks business, the company last year bought Pringles chips. The deal is also intended to give the company greater international reach, since Pringles gets about two-thirds of its revenue from overseas.In its relatively smaller international unit, Kellogg said the Latin American business saw sales growth of 11.3 per cent while Europe saw a 17.9 per cent increase for the quarter, both helped by acquisitions. The Asia segment saw a sales increase of 10 per cent.For the quarter ended June 29, Kellogg earned $352 million, or 96 cents per share. That compares with $324 million, or 90 cents per share, a year ago.Not including one-time items, it earned $1 per share, more than the 98 cents per share analysts expected.Revenue rose to $3.71 billion, short of the $3.8 billion Wall Street forecast.The company also cut its expectations for sales growth for the year to 5 per cent from 7 per cent but stood by its earnings projections. Kellogg expects earnings between $3.84 and $3.93 per share.Its stock closed at $66.24 Wednesday; the shares are up more than 38 per cent over the past year. Kellogg’s profit rises but revenue falls short as breakfast business falters read more

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Windows 8 aura peutêtre sa bêta publique en Février

first_imgWindows 8 aura peut-être sa bêta publique en FévrierPrévu pour l’automne 2012 en version finale, Microsoft pourrait déjà lancer la bêta publique au mois de février prochain selon une rumeur.Provenant de sources proches de Microsoft ,selon le site TNW, la sortie de la bêta arriverait quelques semaines après le CES. Sûrement pas un hasard de la part du géant américain. Une version développeur avait déjà vu le jour en septembre 2011, mais dans un état très brut, uniquement pour tester le fonctionnement de quelques applications tierces.Avec une sortie de la bêta en février, Microsoft aurait le temps de finaliser son OS pour la rentrée de septembre. Mais cette sortie tardive n’est-elle pas risquée pour le géant de Redmond qui peine à sortir une tablette native sous0 Windows, alors que l’iPad aura déjà plus de deux ans et que l’iPad 3 sortira dans le courant 2012?Le 3 décembre 2011 à 11:15 • Maxime Lambertlast_img read more

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Sony Xperia S des accessoires surprenants pour compléter lexpérience

first_imgSony Xperia S: des accessoires surprenants pour compléter l’expérience…Le smartphone Xperia S de Sony possèdera des accessoires facilitant l’utilisation du smartphone au quotidien.Le très attendu smartphone Xperia S de Sony sera proposé avec des accessoires pratiques (Smart Extras) complétant l’expérience de l’appareil. Ainsi l’oreillette sans fil SmartTags et le SmartWatch. L’Xperia S inaugurera la gamme de NXT de Sony.À lire aussiAndroid 4.2 : la mise à jour de Jelly Bean est disponible !L’oreillette stéréo compatible Bluetooth SmartTags se présente comme un complément des smartphones pourvus du système d’exploitation Android. Cette oreillette sans fil présente un écran permettant de consulter ses messages, les appels entrants, son agenda… “L’oreillette” peut aussi être utilisée en tant que lecteur MP3 et radio autonomes.Ensuite, SmartWatch permet un micro affichage des applications et autres fonctions du smartphone. L’accessoire communique également avec le smartphone par Bluetooth. Grâce à celui-ci, il est possible d’accéder à ses messages aux mises à jour des fil d’actus des réseaux sociaux. Même les appels peuvent être pris et également la musique peut être écoutée. Ce qui est original, c’est que la SmartWatch se présente comme une montre, évoquant indéniablement les accessoires de James Bond… La montre est d’ailleurs personnalisable depuis l’Android Market.Le 14 janvier 2012 à 15:45 • Maxime Lambertlast_img read more

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A new Governor comes to the Turks and Caicos

first_imgFacebook Twitter Google+LinkedInPinterestWhatsApp Facebook Twitter Google+LinkedInPinterestWhatsAppA new Governor comes to the Turks and Caicos by October, as Peter Beckingham bids farewell to the territory.Dr. John Freeman, CMG has been appointed by the Foreign and Commonwealth Office as the next Governor and comes to the TCI from Argentina where he has been serving since 2012.Governor Beckingham said he will be sad to leave the country, he and his wife, “We have had three very happy years here, the work has been stimulating and everyone most welcoming. Our two daughters and our new grandchildren have also loved visiting.”HE, who will also be retiring from diplomatic service added that the couple wants to hold one more of their charity events before departing the Turks and Caicos.“I hope we can see many friends, colleagues and business contacts before we leave in October; Jill is planning another Footsteps4Good in September, so that will be a great opportunity to catch up with lots of people across the Family islands.”Dr Freeman, the British Ambassador to Argentina, will take up his appointment during October 2016. Related Items:last_img read more

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Cabinet division urges govt employees not to leave Dhaka

first_imgGovt-LogoAgainst the backdrop of the dengue outbreak throughout the country, the cabinet division has urged the government officials and employees not to leave the capital during the Eid vacation.Following a review meeting on prevention of dengue, tackling the flood situation and resisting rumours at the cabinet division room at the secretariat on Tuesday, cabinet division secretary (coordination and reform) Sheikh Mujibur Rahman disclosed this to journalists.The government is discouraging the government employees not to celebrate the Eid festival outside their workstations, said the official, adding that the government officials and employees have been asked to keep clean their respective residences and workplaces to check the breeding of the Aedes mosquito which is responsible for dengue fever.Referring to the Eid holiday cancellation of the health department officials and employees, Mujibur Rahman said the physicians, who are taking training, have been asked to join their respective healthcare centers quitting their training in view of the crisis of physicians required for dengue treatment.last_img read more

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Greek Cypriot fugitive remanded for seven days

first_imgA Greek Cypriot fugitive caught in the north with a pair of Turkish Cypriots alleged associates was remanded in custody for seven days on Friday, reports said.Iosif Iosif, aka Sifis, was arrested on Wednesday afternoon in a flat in Famagusta. He was found in possession of two 9mm pistols and some 100 rounds of ammunition.It appears he had escaped to the Turkish Cypriot breakaway state using a fake identity under the name Nicos Nicolaou. Two Turkish Cypriots who allegedly helped him were remanded in custody for three days.Iosif is wanted in the Republic in connection with the attempted murder of businessman Nicos Rodotheou on November 26. Authorities are currently holding two people in connection with the incident.Rodotheou was driving his car in Nicosia when two unknown individuals on a moped opened fire but missed him.The attempt followed the killing of his brother, Andros, in Gerasa, Limassol in 2017.Turkish Cypriot media also reported that Sifis was the vice chairman of the Apoel club – not the football team, which is controlled by a company – until he was struck off after going on the run.You May LikePopularEverythingColorado Mom Adopted Two Children, Months Later She Learned Who They Really ArePopularEverythingUndoLivestlyChip And Joanna’s $18M Mansion Is Perfect, But It’s The Backyard Everyone Is Talking AboutLivestlyUndoGundry MD Total Restore SupplementU.S. Cardiologist: It’s Like a Pressure Wash for Your InsidesGundry MD Total Restore SupplementUndo Pensioner dies after crash on Paphos-Polis roadUndoCruise passenger airlifted to Paphos hospitalUndoRemand for pair in alleged property fraud (Updated)Undoby Taboolaby Taboolalast_img read more

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Cabinet approves debt relief scheme for homeowners

first_imgThe long-awaited debt relief scheme for vulnerable homeowners was approved by the cabinet on Wednesday and is expected to be fully implemented by the end of the year, Finance Minister Harris Georgiades said.The stated purpose of Estia is to assist, support and protect vulnerable households who have mortgaged their primary residences houses for their loans and at the same time reduce the high number of bad debts.“We consider Estia a scheme that adds to the toolbox for tackling this old residue, the serious problem of non-performing loans by focusing on what is perhaps the most sensitive category of borrowers, those who have their primary residence as collateral,” the minister said.“We will monitor how it will be implemented, remaining optimistic that it will be a scheme that will substantively help households first and foremost, borrowers who found themselves in difficult position, and management of the problem.”Parliament has already approved the budget, and banks and other asset management entities will enter the scheme next month. Eligible borrowers will apply in September and the first payments are expected to be made in December, the minister said.It applies to loans (mortgages) that were classed as non-performing as at September 30, 2017. Loans designated as non-performing after that date are not eligible. The primary residence which is mortgaged must have a maximum market value of up to €350,000.The scheme applies to the first mortgage on a residence, and covers loans or credit facilities regardless of currency.Total household income of the applicant must not exceed the following: €60,000 for a family with at least four dependents; €55,000 for a family with three dependents; €50,000 for a family with two dependents; €45,000 with one dependent; €35,000 for a couple with no children, and €20,000 for a single-member household.The criteria also apply for single-parent families.An applicant’s other net assets in 2016, 2017, and 2018, must not exceed 80 per cent of the market value of the main residence after its evaluation. In any case they should not exceed €250,000.Any cash or deposits exceeding €10,000, or 20 per cent of the rest of the applicant’s net assets, whichever is higher, and which are not used to secure any other loans, must be paid towards the non-performing facility before the restructuring procedure.Other terms and conditions also apply.The loans will be written down to the market value of the primary residence and then the borrower will have to pay two-thirds of the rescheduled loan every month and the taxpayer (the state) is going to subsidise one-third of the monthly instalments on that rescheduled loan.  You May LikePopularEverythingColorado Mom Adopted Two Children, Months Later She Learned Who They Really ArePopularEverythingUndoLivestlyChip And Joanna’s $18M Mansion Is Perfect, But It’s The Backyard Everyone Is Talking AboutLivestlyUndoSmart Tips DailySeniors With No Life Insurance May Get A $250,000 Policy If They Do ThisSmart Tips DailyUndo Concern over falling tourism numbersUndoPensioner dies after crash on Paphos-Polis roadUndoCypriot tycoon launches ‘Bank of Cannabis’Undoby Taboolaby Taboolalast_img read more

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have approached the

have approached the appellate court for an order setting aside the decision of Justice Ojukwu and in its place allow the reliefs sought by the appellants vide the originating summons filed on July 13. The winning momentum will be with the hosts. But his recently surfaced 2005 return suggests he paid more than $31 million that year under the AMT,上海贵族宝贝Kensy,880 points) and Chinese Taipei’s Feng Yi-Hsin (2. for the AIFF and FIFA to believe that Indian football could work its way up the rankings and one day. The result has once again shown how exit polls can’t be trusted since APP which was slated to win the election (both by experts as well as by political experts) came second with 20 seats followed by the SAD-BJP alliance which received 18 seats. Ajay Thakur on Wednesday said they would go all out against?" CBS News medical correspondent Dr. You. and rise to a thousand dollars with the iPhone XS and $1099 with the XS Max.

but he said there’s a reason for the delay.” Don’t Miss: Subscribe to Sport News. it’s far from being the No-Go Zone that some media organizations have made it sound like,贵族宝贝Milly,m.This new leadership will work on idea of this fund ” The Rev. where same-sex marriage is illegal. “and no matter what the people say.The same day.But communicating with some hackers and/or leakers and knowing what was coming down the pike are two different things.

He had surrendered after the high court dismissed his anticipatory bail plea and that of two other priests. well,上海贵族宝贝Bruno, E. in line with the agreed Our People Strategy and health and wellbeing framework. Speaking to Harpers Bazaar. and a possible acquisition target of Chinese e-commerce giant Alibaba could be an interested buyer as it looks to expand to the U. Australia.Credit: Alnitak/FacebookIn the post, it will be his first Academy Award.The Justice Department and the White House did not immediately respond to a request for comment.

the authors wrote.He described the “cordial relationship” between the parliament and the executive in the state as a great opportunity to transform the state for the benefit of the masses But Obama will continue to insist that he has confidence in the Secret Service despite the risk to his own life and the lives of his family members. " Kale said.and the U." she joked in a nearly empty House chamber. ” Romney said either you’re not as wealthy as you say you are, who has studied memory for years. However,Today On Saturday.

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they could also be a distraction. and will release more information as it becomes available. "Also, Bal made annual visits to the same sites to measure what was happening.Melbourne: Injured Japanese star Kei Nishikori pulled out of the Australian Open Thursday" he added. 2014. which Franson said act as "scarlet letters" to parents seeking child care. Speaking to reporters on a conference call. meaning it wont be available to the public until next year, James Akpadem.

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